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ageing brain

This week on Tuesday at The Canal House Nottingham

Brainergetics

What happens to us as we grow older? At some point do our bodies just run out of energy? Our research is looking at this question. We are comparing the energy producing parts of the brain ‘the mitochondria’ from healthy young and old and diseases connected with advanced age. To help us understand how we might extend the energetic lifespan of our brains we are examining Pipistrelle bat mitochondria. Bats live far longer than their body size and metabolic rate predict, they are ‘exceptionally long-lived’ mammals. Our ultimate aim is to keep the brain running on full batteries until the end.
 LisaChakrabarti

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Epigenetic networks and ageing in 348 mammalian species...including our bats!
New research by a Nottingham academic linking the neurodegenerative disease Parkinson’s to changes in a protein in brain mitochondria is to receive support from a prestigious US funding agency. Dr Lisa Chakrabarti, at The University of Nottingham, will receive $75,000 for a one-year research project from The Michael J. Fox Foundation for Parkinson’s Research (MJFF), which is dedicated to finding a cure for Parkinson’s and funds promising research that could result in new treatments to slow, stop or reverse the progression of the disease. Dr Chakrabarti said: “We are trying to look at mitochondrial biology from a totally different perspective, which could have important implications for Parkinson’s and other neurodegenerative diseases. The funding from The Michael J. Fox Foundation will help us to confirm whether some of the protein changes we see in Parkinson’s are related to disease course.” http://exchange.nottingham.ac.uk/research/parkinsons-study-receives-fu